Vitamin C effective in targeting cancer stem cells

Researchers measure the impact on cancer stem cell metabolism of 3 natural substances, 3 experimental pharmaceuticals and 1 clinical drug.

Vitamin C is up to ten times more effective at stopping cancer cell growth than pharmaceuticals such as 2-DG, according to scientists in Salford, UK.

The research, published in Oncotarget, is the first evidence that Vitamin C (ascorbic acid) can be used to target and kill cancer stem cells (CSCs), the cells responsible for fuelling fatal tumours.

Dr Michael P. Lisanti, Professor of Translational Medicine at the University of Salford, said: "We have been looking at how to target cancer stem cells with a range of natural substances including silibinin (milk thistle) and CAPE, a honey-bee derivative, but by far the most exciting are the results with Vitamin C.

"Vitamin C is cheap, natural, non-toxic and readily available so to have it as a potential weapon in the fight against cancer would be a significant step."

Cancer stem-like cells are thought to be the root cause of chemotherapy resistance, leading to treatment failure in patients with advanced disease and the triggers of tumour recurrence and metastasis (regrowth).

The Salford team set out to assess the bioenergetics of cancer stem cells -- the processes which allow the cells to live and thrive -- with a view to disrupting their metabolism.

Focusing on energy-transfer, they measured the impact on cell lines in a laboratory of 7 substances, the clinically-approved drug stiripentol, 3 natural products -- caffeic acid phenyl ester (CAPE), silibinin and ascorbic acid -- and experimental pharmaceuticals, such as actinonin, FK866 and 2-DG.

While they found that natural antibiotic actinonin and the compound FK866 were the most potent, the natural products also inhibited CSC formation, with Vitamin C, outperforming 2-DG by tenfold in terms of potency.

Vitamin C has previously been shown to be effective as a non-toxic anti-cancer agent in studies by Nobel Prize winner Linus Pauling and was recently shown to reduce mortality by 25% on breast cancer patients in Japan. However, its effects on CSC activity have not been previously evaluated and in this context, it behaves as an inhibitor of glycolysis, which fuels energy production in mitochondria, the "powerhouse" of the cell.

Dr Gloria Bonuccelli, lead author and another member of the Salford team added: "This is further evidence that Vitamin C and other non-toxic compounds may have a role to play in the fight against cancer.

"Our results indicate it is a promising agent for clinical trials, and a as an add-on to more conventional therapies, to prevent tumour recurrence, further disease progression and metastasis."  March 8, 2017 University of Salford

VAXXED

VAXXED

DATE AND TIME

SAT. 5 AUGUST 2017

6:15 PM – 9:00 PM ACST

LOCATION

Secret Venue Adelaide Inner City (Eastern Suburbs) SA 

EVENT 

6:15pm: Doors Open
6:30pm: Film Begins Playing
8:00pm: Film Concludes. Q&A Begins.
(At least TWO of the US VaxXed Team will be joining via skype!)
8:45pm: Q&A Concludes and Film Crew will be present to collect vaccine injury stories.:

US VaxXed Team Can Include: Polly Tommey, Dr. Andrew Wakefield, Del Bigtree, Dr. Brian Hooker, Dr. Suzanne Humphries.

IMPORTANT VENUE INFORMATION:

Due to the well orchestrated threats of violence and abuse that come from the pro-censorship community, the exact venue will be announced to ticket holders via email and/or sms 2 hours prior to the event. If you do not receive this notification by 4:35pm on Saturday August 5th, please email auspress@vaxxedthemovie.com immediately. 

The general location of the venue is Adelaide inner city, Eastern side. 

TICKETING QUESTIONS:

CONCESSION: Proof of concession is required upon entry. 

- Children (Under 16)
- Students (where the category of study qualifies for concession on public transportation)
- Pension Recipients of Disability Payment, Carers Payment, Aged Payment.
- Health Care Card Holders

SMALL CHILDREN & TICKETING:

Infants and small children who can and will comfortably be seated on their parent/caregiver's lap for the duration of the film do not need a ticket to be purchased. Small children and older children who will require their own seat for some or all of the film, need to have a ticket purchased.

ABOUT VAXXED:

In 2013, biologist Dr. Brian Hooker received a call from a Senior Scientist at the U.S. Centers for Disease Control and Prevention (CDC) who led the agency’s 2004 study on the Measles-Mumps-Rubella (MMR) vaccine and its link to autism.

The scientist, Dr. William Thompson, confessed that the CDC had omitted crucial data in their final report that revealed a causal relationship between the MMR vaccine and autism. Over several months, Dr. Hooker records the phone calls made to him by Dr. Thompson who provides the confidential data destroyed by his colleagues at the CDC.

Vaxxed: from Cover-Up to Catastrophe is a documentary film that compiles this information together, and interviews a range of medical doctors, university professors, and autism specialists. 

To learn more about the film, the evidence, and to view the trailor, please visit: www.vaxxedthemovie.com

IS THIS DOCUMENTARY ANTI-VACCINATION?

No. The documentary makes the following four calls to action:

1. That Congress subpoena Dr. William Thompson and investigate the CDC fraud.

2. That Congress repeal the 1986 National Childhood Vaccine Injury Act and hold manufacturers liable for injury caused by their vaccines.

3. That the single mealses, mumps, and rubella vaccine be made available immediately. 

4. That all vaccines be classified as pharmaceutical drugs and tested accordingly. 

- Being pro Government transparancy is not anti-vaccination. 

- Being pro large corporations paying their own lawsuit bills is not anti-vaccination.

- Being pro availbaility of safer vaccines that achieved the same immunity outcomes is not anti-vaccination.

- Being pro correct classification and testing of vaccines is not anti-vaccination.

Watch the documentary, and make your own judgement about its stance. 

VIEWER DISCRETION:

This documentary contains adult language and themes. Some images and scenes may be distressing to some viewers. Viewer discretion is advised.

WARNING:

** RESELLING TICKETS FOR A PROFIT IS NOT ACCEPTABLE. ORGANIZERS MAY REFUSE ENTRY TO TICKET HOLDERS WHO ENGAGE IN TICKET RESELLING FOR A PROFIT. **

Toxic Chemicals in the Home

We all know how dangerous toxins can be to our health and well being.  Sadly, your body may be a toxic waste dump and you don’t even realise it.  Eighty thousand toxic chemicals have been released since the industrial revolution and few of them have been tested to find out the effect they have on our health; or how long they remain in our environment.  The average newborn baby has up to 287 known toxins in their umbilical cord blood.  Can you imagine how many toxins we are therefore exposed to during our lifetime.  It is vitally important that we regularly detoxify our bodies to stay on top of the onslaught of these chemicals as we are simply not designed to handle the amount we are exposed to.

Here are a few common symptoms of toxicity:

Fatigue, muscle and joint aches, sinus problems, bloating and gas, constipation/diarrhoea, foul smelling stools, heart burn, insomnia, dark circles under the eyes, rashes, inability to lose weight, anxiety and so much more.

So how do you detoxify?

Remember the tortoise and the hare.  Detoxifying needs to be done slowly and carefully so as not to overwhelm your body and put more of a burden upon it.  Simply things like:

1.    1½ litres minimum of clean fresh water daily.

2.     Avoid gluten, dairy, sugar and yeast to repair you gut for when you start to clean out your liver.  Rushing a liver detox with an inflamed, leaky bowel is a recipe for disaster. 

3.    Take regular infrared saunas to assist you to sweat it out slowly.

4.    Throw away all the toxic cleanser you use in your home.   Young Living has some amazing cleaning products especially Thieves.

5.    Quit smoking.

6.    Cut right back on your alcohol. Have a completely alcohol free month.

7.    Walk daily in a park – not along a busy road where you are breathing in even more toxins.  Every weekend take on a long walk in the country.  If short on time climb Mt Lofty and make your lungs breathe in the fresh air provided by the canopy of trees.

8.    Have a regular massage to get your lymphatics clearing the toxins from the tissues.

9.    Get a minimum of 8 hours sleep every night as our body does most of our detoxification during sleep.

10. Eat organic food.

11. Place indoor plants in your home as they have been proven to remove toxins from the atmosphere.

12. Make an appointment at The House of Healing to establish the level of toxins and the stress on each of your organs. We will also organise a suitable product to clean out your liver slowly and gently. Remember the tortoise………

The Environmental Working Group (EWG) recently released a list of high-priority chemicals which may be found in our homes. Here are the top 10.

1. Asbestos

This is a carcinogen, found in automobile brake pads and clutches, vinyl tiles, and roofing materials. News reports have recently revealed that asbestos is still being used legally in Australian building materials.

2. PERC - Perchloroethylene or Tetrachlorethylene

This is a potential carcinogen with links to numerous cancers. It is used in dry-cleaning fluids, water repellents, paint removers, printing inks, glues, sealants, polishes and lubricants.

3. Phthalates

Also called plasticisers, this group of chemicals is linked to reproductive harm and early puberty in girls. They are found in PVC, plastic wraps, toys, vinyl flooring, adhesives, detergents, lubricating oils, automotive plastics, garden hoses, blood storage containers, medical tubing, plastic clothes like raincoats and personal-care products including soaps, shampoos, hair sprays and nail polishes.

4. BPA - bisphenol A

Used in the lining of food cans, plastic food containers, tetra packs, plastic and baby bottles, plastic dinnerware and cash register receipts, BPA is carcinogenic and an endocrine disrupter with links to infertility, development risks and diabetes.

5. Chlorinated phosphate fire retardants

With links to possible brain and nerve damage, these chemicals are found in upholstered furniture, foam cushions, infant car seats and insulation.

6. TBBPA - Tetrabromobisphenol A

TBBPA is a flame retardant with potential carcinogen and endocrine disruption properties. It is found in electronic equipment, auto parts and appliances.

7. Brominated phthalate fire retardants

Found in polyurethane foam for furniture and baby products, these chemicals are linked to developmental toxicity.

8. I-Bromopropane - IBP or n-propyl bromide

This is found in degreasers and cleaners, spray adhesives, aerosol cleaners, spot removers, coin cleaners, paintable mould release, automotive refrigerant flushes and lubricants. It may have adverse development and reproductive effects.

9. DEHA - Diethylhydroxylamine

This probable carcinogen is also linked to developmental toxicity and is found in plastic wrap and PVC plastic.

10. P-dichlorobenzene

This is mainly used in deodoriser blocks in domestic and public toilet facilities. It is also used as a domestic air freshener, in moth balls, and has some uses in the pharmaceutical industry. It is linked to liver and nerve damage. 

Your Health - Our Passion